FIRST US BANK Share: Banks & Credit Unions FIRST US BANK Visit Website 3291 US Highway 280, Ste 100 Birmingham, AL 35243 (205) 582-1202 About Map About First US Bank is an independent community bank based right here in Alabama. We offer great rates and a full array of financial products and digital services to meet the way you bank today. What's Nearby? Distance: 5 10 15 20 25 50 mi.